Some information provided by the Mayo Clinic.

A C-reactive protein test measures the concentration in blood serum of a special type of protein produced in the liver that is present during episodes of acute inflammation or infection.

High-sensitivity C-reactive protein (hs-CRP) test takes the traditional cardiac check-up a step further, pinpointing those people who are at a much higher risk than others for heart disease, America’s leading cause of death. From hs-CRP results, doctors gain crucial insight into inflammation of the blood vessels around the heart, a factor not considered until recently for patients at risk. According to the American Heart Association, an hs-CRP test is most useful for people who have an intermediate risk (a 10 to 20 percent chance) of having a heart attack within the next 10 years. This risk level, called the global risk assessment, is based on lifestyle choices, family history and current health status.

The Risk

If you are planning on getting a test, we have good news! The hs-CRP has very little risk. You may have tenderness or soreness around the draw site and rarely ever gets infected.

How You Prepare

There are no particular preparations needed for either a standard CRP test or an hs-CRP test. However, if your blood is being drawn for other tests, your doctor will tell you if you need to fast or follow other instructions. Be sure to ask your doctor if you’re having other tests at the same time.

Some medications can affect your CRP level. Tell your doctor about any medications you take.

During the Procedure

Blood is drawn from a vein, usually from your arm. Before the needle is inserted, an elastic band around your upper arm causes the veins in that arm to fill with blood, and the puncture site is cleaned with antiseptic.

After the Procedure

After your CRP test, you should be able to drive yourself home and do your normal activities. It may take a few days for you to get your results back. Your doctor should explain to you what the results of your test mean. If you’re having an hs-CRP test to help find out your heart disease risk, keep in mind that your CRP level is only one risk factor for coronary artery disease.

Your doctor will discuss what your CRP test result means.

If you’re having an hs-CRP test to evaluate your risk of heart disease, these are the current risk levels used:

  • Low risk. You have a CRP level of less than 1.0 milligram per liter (mg/L).
  • Average risk. You have a CRP level between 1.0 and 3.0 mg/L.
  • High risk. You have a CRP level greater than 3.0 mg/L.

Remember that high levels of CRP are caused by infections and many long-term diseases. Contact us if you have any questions or to set up an appointment.